New Co-author Publication: Hic1 maintains chromosomal stability independent of p53

Great news, we have a new co-author publication out in the journal Oncogene! The work was lead by Professor Neil Watkins, and is titled "The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53". You can access the full article here [Link] ABSTRACT: Hypermethylated-in-Cancer 1 (Hic1) is a tumor suppressor gene frequently inactivated by epigenetic silencing and loss-of- heterozygosity in…

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New Co-Author Publication in Gut: CDK4 inhibitors for treatment of Pancreatic Cancer

More great news, we have another co-author publication in the outstanding journal Gut. This fabulous work was pioneered by the very talented Dr Marina Pajic and her group at the Garvan Institute. We were very honoured to be involved in such amazing work. The title of the publication is "Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of…

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New Co-Author Publication! Ensa controls S-phase length by modulating Treslin levels.

Great news, we have published a co-authored paper entitled 'Ensa controls S-phase length by modulating Treslin levels' in the prestigious journal 'Nature Communications'. This work was started back in 2011 when I was a Post-Doc in the laboratory of Anna Castro in France. It's exciting to see those inital discoveries transition into the finished paper. The article is Open Access and…

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New Publication in Cell! The Phosphoregulation of Mitosis

We are incredibly excited to announce that our SnapShot is out today in Cell! This snapshot of mitosis collates hundreds of phosphorylation events and directly links them with their regulatory kinases and counterbalancing phosphatases, in both time and space, in a highly innovative 'circtanglar' cell layout. More importantly, the static PDF version is accompanied by an interactive website that enables users…

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New Publication: Hedgehog signaling in small cell lung cancer

Great news we have a new co-author publication in Oncogene! This work was in collaboration with Prof. Neil Wakins here at the Garvan Institute and focuses on the role of Hedgehog (Hh)  signaling in small cell lung cancer (SCLC). Small cell lung cancer is a common, aggressive malignancy with universally poor prognosis. Full details can be found here [link] TITLE: "The role…

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New Review Published “The role of MDM2 and MDM4 in breast cancer development and prevention”

Great news, we have had a co-author review published in the Journal of Molecular and Cellular Biology. You can check out the full review here. Abstract The major cause of death from breast cancer is not the primary tumour, but relapsing, drug-resistant, metastatic disease. Identifying factors that contribute to aggressive cancer offers important leads for therapy. Inherent defense against carcinogens…

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8th Garvan Signalling Symposium – Registration Now Open !!!

8th Garvan Signalling Symposium  Date: Monday 31st of October and Tuesday 1st of November 2016 Venue: The Garvan Institute of Medical Research, Sydney Registration - Abstract submission to 15th of September 2016  The Garvan International Signalling Symposium is a premier meeting focused on the mechanisms of signal transduction. It began as a small meeting organised by Prof. Roger Daly around the…

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