New Review: The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma

Very excited to announce a new review from our PhD student Tom Johnson, in collaboration with Glen Reid's laboratory, has been accepted and published in Frontiers in Cell and Developmental Biology. Its an excellent, comprehensive review of of the oncoprotein YB-1 in Lung Cancer and Mesothelioma. The review article is Open Access and free for everyone to download. Lung cancers…

0 Comments

Congratulations to Tom, runner up in the three-minute thesis final

Thomas Johnson, far left. Runner up 3MT winner A big congratulations to our PhD student Tom Johnson (pictured far left) who was the runner-up at the recent University of Sydney Faculty of Medicine and Health (FMH) three-minute thesis final. He will be representing FMH in the University of Sydney Final on 20 August, 2019. Tom’ talk: Patients suffering mesothelioma are afforded…

0 Comments

How to analyse single cells time-lapse movies using Fiji and/or Photoshop

In the following powerpoint tutorial I run through how you can use ImageJ/FIJI to import your raw microscopy image files and then analyse and track individual cells to generate single cell fate maps. Note, unless you are also planning on quantifying fluorescent intensity data in your movies, I strongly suggest converting all of your image files to high quality JPEGs…

0 Comments

New Publication: The Oncogenic Functions of MASTL Kinase

I am very excited to announce our new review paper which is out now in Front Cell Dev Biol [Link]. This is also the first paper from Dr Kamila Marzec who recently joined the lab. Great work! MASTL kinase is a master regulator of mitosis, essential for ensuring that mitotic substrate phosphorylation is correctly maintained. It achieves this through the phosphorylation…

0 Comments

New Co-Author paper out now in SciTransMed: Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

Very exciting day to see this amazing work by the lab of Prof.Neil Watkins published in the prestigious Science Translational Medicine Journal. A huge amount of work for a lot of very talented people over many many years went into this study, and hopefully it will result in significant improvements for the treatment of lung cancer patients using platinum based…

0 Comments

New Co-Author paper: The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

  Great news, we have recently published a co-author paper in collaboration with Darren Saunders Lab entitled "The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia". The work was pioneered by a very talented student (now Doctor), Robert Shearer.   You can access the full article here [Link] ABSTRACT Primary cilia are crucial for signal transduction in a…

0 Comments

New Paper Published: MASTL overexpression promotes chromosome instability and metastasis in breast cancer

Very excited to announce that our latest paper entitled "MASTL overexpression promotes chromosome instability and metastasis in breast cancer" has just been published online with Oncogene. You can access the full article for free here:https://www.nature.com/articles/s41388-018-0295-z Abstract MASTL kinase is essential for correct progression through mitosis, with loss of MASTL causing chromosome segregation errors, mitotic collapse and failure of cytokinesis. However,…

0 Comments

Research Position (Full-time) Available Now.

Great news, we are looking for a full-time research assistant or junior post-doctoral researcher. We are seeking a highly motivated BSc (Hons) graduate who is interested in pursuing a career in biomedical research with particular focus on cancer cell biology. The successful applicant will have demonstrated a high level of undergraduate achievement and applicants graduating with Honours will be highly regarded.…

0 Comments